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Targeting Wnt signaling to solve the dental pulp challenge6:34 Dental pulp regeneration remains a major clinical challenge. Researchers have discovered that SMAD7 directly forms a transcriptional complex with β-catenin in human dental pulp stem cells, activating Wnt signaling and promoting regenerative gene expression. New peptide fragments teach the gut to tolerate food6:01 In little moments like when sipping coffee or licking an ice cream cone, it doesn't seem like your body is pulling off a biological miracle. But it is. That cookie is not you-yet when you put it in your mouth, your body is able to tolerate it and process it without any detriment to your health in a process called oral tolerance. How does the human body make that decision between tolerance and rej… Report highlights gaps in cancer care access for tribal citizens17:25 The University of Oklahoma's Native Nations Center for Tribal Policy Research recently released a new Sovereign Report titled "Purchased/Referred Care and Cancer: Overview and Options for Tribal Consideration." Post amputation pain differs with movement and prosthetic type17:25 Researchers at the University of Colorado Anschutz have identified a critical gap in how post-amputation pain is evaluated and treated. State bans on prior authorization show limited impact on buprenorphine treatment retention14:04 State laws that ban insurance prior authorization for buprenorphine-a leading medication for opioid use disorder-may not help more patients stay in treatment for the recommended minimum of 180 days, Weill Cornell Medicine researchers report. Meaning, purpose and spirituality should be core parts of healthcare, say experts7.března A new peer-reviewed paper calls for meaning, purpose, and spirituality to be treated as core components of lifestyle medicine - not optional add-ons - because they directly influence patients' ability to adopt and sustain health-promoting behaviors. Biomimetic smart insole system enables accurate gait monitoring7.března With the increasing aging population, high incidence of chronic diseases, and the growing number of congenital or acquired foot deformities, lower limb dysfunction and abnormal gait problems are becoming increasingly common, posing a significant threat to public health and quality of life. New report shows primary care readiness for digital cognitive assessment tools6.března A new Gerontological Society of America (GSA) report summarizes survey findings on the readiness of the primary care workforce to adopt digital cognitive assessments (DCAs) for use in the diagnostic process for cognitive impairment and dementia. Buck Institute launches a new initiative to measure and extend human healthspan6.března The Buck Institute for Research on Aging today announced the launch of Healthspan Horizons, a new initiative designed to address one of the most urgent challenges in modern medicine: how to measure, understand, and extend healthspan-the years of life spent in good health. Seniors defy stereotypes of decline through positive mindsets6.března Aging in later life is often portrayed as a steady slide toward physical and cognitive decline. But a new study by scientists at Yale University suggests an alternate narrative - that older individuals can and do improve over time and their mindset toward aging plays a major part in their success. |